Unit I: Pharmacology of Drugs Acting on the Cardio-Vascular System
Pharmacology of drugs acting on cardio-vascular system
Introduction to hemodynamic and electrophysiology of heart Drugs used in congestive heart failure.
Anti-hypertensive drugs.
Anti-anginal drugs.
Anti-arrhythmic drugs.
Anti-hyperlipidemic drugs.
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Unit II: Pharmacology of Drugs Acting on the Cardio-Vascular and Urinary System
Pharmacology of drugs acting on cardio vascular system:
Drug used in the therapy of shock.
Hematinics, coagulants and anticoagulants.
Fibrinolytics and anti-platelet drugs.
Plasma volume expanders.
Pharmacology of drugs acting on urinary system:
Diuretics.
Anti-diuretics.
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Unit III: Autacoids And Related Drugs
Autacoids and related drugs:
Introduction to autacoids and classification of Histamine, 5-HT and their antagonists.
Prostaglandins, Thromboxanes and Leukotrienes.
Angiotensin, Bradykinin and Substance P.
Non-steroidal anti-inflammatory agents.
Antigout drugs, Anti rheumatic drugs.
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Unit IV: Pharmacology of Drugs Acting on the Endocrine System
Pharmacology of drugs acting on endocrine system:
Basic concepts in endocrine pharmacology.
Anterior Pituitary hormones- analogues and their inhibitors.
Thyroid hormones- analogues and their inhibitors.
Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin D.Insulin, Oral Hypogl ycemic agents and glucagon. ACTH and corticosteroids.
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Unit V: Pharmacology of Drugs Acting on the Endocrine System and Bioassay
Pharmacology of drugs acting on endocrine system
Androgens and Anabolic steroids. Estrogens, progesterone and oral contraceptives. Drugs acting on the uterus.
Bioassay:
Principles and applications of bioassay. Types of bioassay.
Bioassay of insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine and 5-HT.
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