PHARMACEUTICAL ORGANIC CHEMISTRY - 3

Unit I: Stereo Isomerism

Stereo isomerism: Optical isomerism– Optical activity, enantiomerism, diastereomerism, meso compounds. Elements of symmetry, chiral and achiral molecules. DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers. Reactions of chiral molecules. Racemic modification and resolution of racemic mixture. Asymmetric synthesis: partial and absolute.