MEDICINAL CHEMISTRY - 2
Unit I: Antihistamines, Proton Pump Inhibitors, Antineoplastic Agents, Antimetabolites And Antibiotics
Antihistaminic agents: Histamine, receptors and their distribution in the human body. H1–antagonist: Diphenhydramine hydrochloride*, Dimenhydrinate, Doxylamine succinate, Clemastine fumarate, Diphenylpyraline hydrochloride, Triphelenamine hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine hydrochloride, Chlorpheniramine maleate, Triprolidine hydrochloride*, Phenidamine tartrate, Promethazine hydrochloride*, Trimeprazine tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrizine Cromolyn sodium. H2-antagonists: Cimetidine*, Famotidine, Ranitidine. Gastric proton-pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole. Anti-neoplastic agents: Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan, Chlorambucil, Busulfan, Thiotepa. Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate*, Azathioprine. Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin. Plant products: Etoposide, Vinblastine sulphate, Vincristine sulphate. Miscellaneous: Cisplatin, Mitotane.
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